Protective Effect of Different Infusion Schemes on Lung in Children Undergoing Open Heart Surgery
LIUJia-peng,YANG Jin-bin,HAN Jian-ge
Tianjin Chest Hospital, Tianjin Cardiovascular Diseases Institute, Tianjin,300352, China.
Abstract:
Objective To investigate the pulmonary protective effect of different infusion schemes on children with ventricular septal defect (VSD) after repair. Methods 70 children who underwent ventricular septal defect repair in our hospital from January 2017 to December 2020 were randomly divided into two groups:crystalloid infusion group and 5% albumin infusion group, with 35 children in each group. Arterial blood gas analysis results, intraoperative volume, cardiopulmonary bypass time, aortic occlusion time, mechanical ventilation time, ICU stay time and total hospitalization time at different time points were recorded. Results The infusion volume and red blood cell volume of 5% albumin infusion group were lower than those of crystalloid infusion group (P < 0.05); The mechanical ventilation time and ICU stay time of 5% albumin infusion group were shorter than those of crystalloid fluid infusion group (P < 0.05). The level of alveolar arterial oxygen differential pressure(A-aDO2) in 5% albumin infusion group was lower than that in crystalloid infusion group at T2 and T3 (P< 0.05). Conclusion The application of 5% albumin injection in the repair of ventricular septal defect in children can significantly improve the value of A-aDO2, reduce the application of intraoperative fluid and shorten the time of mechanical ventilation.
