Construction and Verification of Sepsis Risk Factors after Ureteroscopic Lithotripsy
YAN Chao，WANG Shu-sheng，GONG Shu
Abstract:
Objective To construct a combine predictor and verify its predictive efficacy by analyzing the risk factors of sepsis associated with ureteroscopic lithotripsy (URL). Methods 250 patients with ureteral calculi who underwent ureteroscopic lithotripsy admitted to the department of urology in our hospital from January 2016 to June 2021 were analyzed retrospectively. The observation group with sepsis (n=50) and the control group without sepsis (n=200) were divided. The general data of the two groups were analyzed by univariate and Logistic multivariate analysis, the receiver operating characteristic (ROC) curve was drawn, the area under the curve (AUC) was calculated, the joint predictor was constructed through the regression coefficient of independent risk factors and the cut-off point was calculated. It was applied to another group of 30 patients with ureteral calculi for ureteroscopic lithotripsy to verify its prediction efficiency. Results Single factor analysis showed that diabetes, urine leukocyte (UWB), percentage of blood neutrophils (N%), ureteral calculi location and length of stones were correlated with sepsis (P<0.05). Multivariate analysis of diabetes, urine leukocytes, blood neutrophil percentage (N%) and ureteral stone location were independent risk factors for ureteral lithotripsy with sepsis (P<0.05). Risk score = 0 . 741×Diabetes+ 0 . 651×Urinary
