External Application of Shuangbai Powder in the Treatment of Patients with Surgical Acute Abdomen:a Meta-analysis of Randomized Clinical Trials
LIANG Yong-xin,ZHOU Shu-yi,ZHAO Xian-ming
Guangzhou University of Traditional Chinese Medicine, Guangzhou(510000), China
Abstract:
Objective To systematically evaluate the clinical efficacy of Shuangbai Powder in the treatment of surgical acute abdomen. Methods The randomized controlled trial (RCT) of external application of Shuangbai powder in the treatment of surgical acute abdomen was searched from the date of establishment of CNKI, Wan Fang, VIP, Web of Science, PubMed and EMbase databases to May 2020. The literatures were collected strictly according to inclusion and exclusion criteria. Cochrane RevMan 5.3 was used for the metaanalysis. Results A total of 10 randomized controlled trials of clinical research literatures and 733 patients were included. Compared with the control group, treatment group had a better efficacy in total effective rate of surgical acute abdomen [OR=6.62, 95%CI(3.65,12.00), P<0.001]. The relief of abdominal pain in the treatment group was more significant than that in the control group [MD=-1.67, 95%CI (-1.85,-1.49), P<0.001]. The recovery time of white blood cell count in the treatment group was shorter than that of the control group [MD= -2.38, 95%CI (-2.77,-2.00), P<0.001], which was statistically significant. Conclusion Shuangbai powder has certain advantages in treating surgical acute abdomen, but it still needs to be confirmed by multicenter, large-sample, high-quality RCT studies.
