Efficacy Analysis of Adenosylmethionine Combined with Compound Ganhuangcao in Treating Cholestatic Liver Injury Caused by Biliary Obstruction
Xia Ya-fei,Yan Shu
Tianjin NanKai Hospital, Tianjin 300100,China
Abstract:
Objective To investigate the clinical effect of adenosylmethionine combined with compound herbal medicine on cholestatic liver injury caused by biliary obstruction. Methods A total of 70 patients with cholestatic liver injury caused by biliary obstruction treated in our hospital from October 2018 to April 2019 were selected, and the patients were divided into the control group and the observation group according to the random digital table method. Control group was treated with adenosylmethionine, and the observation group was administrated with compound herbal medicine on the basis of that above. The clinical efficacy, liver function and inflammatory factors of the two groups were compared. Results After treatment, serum bilirubin (DBIL),total cholesterol (CHOL), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bile-The levels of erythroglobin (TBIL) and indirect bilirubin (IBIL) were significantly improved (P<0.05), and the observation group was better than those of the control group. The levels of white blood cell count (WBC) and C-reactive protein (CRP) in the two groups of patients were significantly reduced (P <0.01), while the levels of decline in the observation group were more significant than those of the control group (P <0.05). There were no significant difference in the levels of IgA, IgE and Ca2+ in the serum of patients in the control group and the observation group compared with those before treatment (P >0.05). Conclusion Adenosylmethionine combined with compound herbal medicine can effectively alleviate the clinical symptoms of cholestatic liver injury caused by biliary obstruction and it can improve liver function and reduce inflammation level in patients.
