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桃红四物汤联合髋关节置换术治疗老年股骨颈骨折的临床研究
王阳,叶松庆,李永全
天津市泰达医院骨科天津 300457
摘要:
目的:探讨对老年股骨颈骨折患者应用桃红四物汤联合髋关节置换术治疗的疗效。方法:选取我院 2018年 7 月—2020年 2月收治的 85例老年股骨颈骨折患者,依据治疗选择的方法不同,分为观察组(应用髋关节置换术 +术后常规治疗与桃红四物汤中药, 43例)和常规组(应用髋关节置换术 +术后常规治疗, 42例);评价两组术前及术后 12周的血清相关指标胰岛素生长因子 -1(IGF-1)、分泌型蛋白骨硬化蛋白( SOST)水平、骨密度(股骨颈、 Wards三角区、大转子)、髋关节功能 Harris评分、步行能力评分、肢体运动功能 FMMS评分及并发症发生情况。结果:术前两组血清 IGF-1、 SOST水平、股骨颈、 Wards三角区、大转子三个部位的骨密度、 Harris评分、步行能力评分、 FMMS评分比较均无明显差异(P> 0.05)。术后 12周,观察组血清 IGF-1水平、股骨颈、 Wards三角区、大转子三个部位的骨密度含量、 Harris评分及 FMMS评分均高于常规组;观察组血清 SOST水平、步行能力评分均低于常规组;观察组下肢静脉血栓、假体松动等并发症发生率均低于常规组,差异均有统计学意义( P< 0.05)。结论:老年股骨颈骨折患者应用桃红四物汤联合髋关节置换术治疗,不仅能加快骨折的愈合与髋关节功能的恢复,还能减少下肢静脉血栓、假体松动等并发症发生比例,提升临床疗效,有一定的临床价值。
关键词:  股骨颈骨折  血清指标  桃红四物汤  老年  髋关节置换术
DOI:10.3969/j.issn.1007-6948.2020.05.016
投稿时间:2020-04-21
基金项目:
Study on Taohong Siwu Decoction Combined with Hip Arthroplasty in the Treatment of Elderly Femoral Neck Fractures
WANG Yang,YE Song-qing,LI Yong-quan
Department of Orthopaedics, Tianjin Teda Hospital, Tianjin 300475, China
Abstract:
Objective To investigate the effect of Taohong Siwu Decoction combined with hip replacement surgery on elderly patients with femoral neck fractures and its effect on serological parameters, bone density, functional recovery and complications. Methods All clinical data of 85 elderly patients with femoral neck fractures during the period from July 2018 to February 2020 in general surgery were retrospectively analyzed. According to different treatment options, they were divided into observation groups (applying hip replacement surgery routine treatment with Taohong Siwu Decoction, 43 cases) and routine group (applying hip replacement surgery routine treatment after surgery, 42 cases). Evaluate the correlation between the two groups of serum before and after surgery. Indicators: Insulin growth factor-1 (IGF-1), secreted protein osteosclerin (SOST) level, bone density (femoral neck, Wards triangle, trochanter), Harris function hip score, walking ability score, limb Motor function FMMS score and complications. Results There were no differences in the levels of serum-related indicators, bone mineral density, Harris score, walking ability score, FMMS score and complications in the two groups before surgery (P>0.05). At 12 weeks after surgery, the serum IGF-1 levels, bone mineral density, Harris score and FMMS scores in the observation group were higher than those in the conventional group; serum SOST levels and walking ability scores in the observation group were lower than conventional group. The number of complications such as lower extremity venous thrombosis and internal fixation loosening in the conventional group were higher than those in the observation group, with statistical differences (P<0.05). Conclusion The application of Taohong Siwu Decoction combined with hip replacement surgery in elderly patients with femoral neck fractures can not only accelerate fracture healing and hip function recovery, but also reduce the number of complications such as lower extremity venous thrombosis and loosening internal ?xation. To improve clinical ef?cacy, it has certain clinical value.
Key words:  Femoral neck fracture  serum index  TaoHong SiWu decoction  the elderly  hip replacement

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