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益气散结方联合疏肝解郁胶囊对甲状腺癌术后患者的影响
胡鸣旭,朱雪莲
肿瘤科;妇科哈尔滨150001
摘要:
目的:观察益气散结方联合疏肝解郁胶囊对甲状腺癌术后患者免疫功能、生活质量及抑郁状态的改善作用。方法:将60 例甲状腺癌术后患者随机均分为两组,对照组和治疗组,每组30 例,对照组接受左甲状腺素钠和疏肝解郁胶囊治疗,治疗组在对照组的基础上加用益气散结方,观察比较两组患者血清中5- 羟色胺、多巴胺水平及T 淋巴细胞亚群、抑郁评分、生活质量评分水平。结果:治疗后,治疗组血清5- 羟色胺、多巴胺水平明显高于对照组(P <0.05),血清CD3+、CD4+ 水平明显高于对照组(P <0.05),治疗组抑郁评分HAMD 及SDS 水平明显低于对照组(P <0.05),治疗组生活质量评分明显高于对照组(P <0.05)。结论:益气散结方联合疏肝解郁胶囊可有效提高甲状腺癌术后患者血清5- 羟色胺和多巴胺水平,提高患者免疫功能,降低抑郁评分,提升生活质量,促进患者术后恢复。
关键词:  益气散结方  疏肝解郁胶囊  甲状腺癌  免疫功能  抑郁状态
DOI:10.3969/j.issn.1007-6948.2020.04.010
投稿时间:2019-11-13
基金项目:黑龙江中医药中青年科技攻关项目(ZQJ-053)
Effect of YiqiSanjie Decoction Combined with ShuganJieyu Capsuleon the Patients with Thyroid Cancer after Operation
HU Ming-xu,ZHU Xue-lian
Department of Cancer, Heilongjiang Academy of Chinese Medicine, Harbin (150001), China
Abstract:
Objective To study the effect of YiqiSanjie Decoction combined with ShuganJieyu capsule on the improvement of immune function, life quality and depressed state of patients with thyroid cancer after operation. Methods 60 cases of thyroid cancer patients, according to themethod of random grouping, would be divided into thecontrol group and the treatment group, with each group 30 cases. The control group were treated with Levothyroxine sodium and ShuganJieyu capsule. On the basis, the treatment group added oral administration of YiqiSanjie Decoction. The levels of serum 5-HT, DA, T lymphocyte subsets, depression score and quality of life score were compared. Results At the end of the treatment, the levels of serum 5-HT and DA in the treatment group were significantly improved than those of the control group (P <0.05). Thelevelsof CD3+ and CD4+in the treatment groupwere significantly higher than those of the control group (P <0.05). The levels of HAMD and SDS in the treatment group were obviously lower than those of the control group (P <0.05). And thescores of the quality of life in the treatment group were significantly higher than those of the control group(P <0.05). Conclusion YiqiSanjie Decoction combined with ShuganJieyu capsule can significantly improve the levels of serum 5-HT and DA of patients with thyroid cancer after operation. It can improve the immune function, reduce depression scores, improve the patient' s depression and quality of their life as well as promote postoperative recovery of patients.
Key words:  YiqiSanjie decoction  ShuganJieyu capsule  thyroid cancer  immune function  depressed state

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