Effect of QiangJinBuGu Decoction combined with PFNA assisted by C-arm on PLT, D-D and IL-13 Levels in Patients with Intertrochanteric Fracture of Femur
REN Zheng,WANG Zai-peng,OU Fu-nian
Jinsha County Traditional Chinese Medicine Hospital, Jinsha 551800, China
Abstract:
Objective To investigate the effect of Qiangjin bugu decoction combined with C-arm assisted proximal femoral anti-rotation intramedullary nail internal fixation (PFNA) on the levels of platelet count (PLT),D-Dimer (D-D) and interleukin-13 (IL-13) in patients with intertrochanteric fractures. Methods 120 cases of femoral intertrochanteric fractures treated in our hospital from March 2016 to March 2018 were recorded as observation objects. They were divided into study group and control group by random drawing. The control group was treated with PFNA surgery assisted by C-arm, while the study group was treated with Qiangjin bugu decoction on the basis of the control group. The postoperative recovery of the two groups, the recovery of hip joint and knee joint in different time periods, the PLT, D-D and IL-13 levels before and after surgery and the postoperative complications were compared respectively. Results The study group of the time of movement in bed[(3.84±0.56) d], fracture healing time[(113.88±14.89) d] and time under full load[(130.22±17.39)d] were lower than the control group of [(6.02±0.87) d], [(150.82±19.85) d], [(194.73±21.75) d] ( P <0.05). The scores of hip joints at 3rd, 6th and 12th months after surgery were [(64.27±8.14)], [(71.60±9.22) ]and [(78.13±9.27)], and the scores of knee joints were [(88.41±11.48)], [(94.17±13.06)] and[(98.27±14.32)] in the study group, which were higher than those in the control group of [(52.09±6.23)], [(58.54±6.39)], [(64.01±7.26)], [(79.05±9.33)], [(84.07±9.33)] and [(90.25±13.95) ] (P < 0.05). The PLT [(225.18±14.28)×109/L], D-D [(92.35±35.28) μg/ml] and IL-13 levels [(13.58±2.03) pg/ml] at the 7th day after surgery were lower in the study group than those in the control group of [(234.75±15.06)×109/L], [(109.66±36.83) μg/ml] and [(19.24±3.48) pg/ ml] (P < 0.05). The incidence of infection, pressure ulcers, deep vein thrombosis and fracture nonunion observed between the study group and the control group were no signi?cant differences (P > 0.05). Conclusion The effect of Qiangjin bugu decoction combined with PFNA assisted by C-arm in the treatment of femoral intertrochanteric fracture is signi?cant, which is conducive to promoting the recovery of knee joint and hip joint function, and improving the levels of PLT, D-D and IL-13. It is worthy of clinical application.
