Effects of Xuanbai Chengqi decoction combined with nutritional support on the nutritional status and gastrointestinal function of patients after colorectal cancer surgery
CHEN Zhi-fei,SUN Wei-tao,YAN Ting-qi
Abstract:
Objective To explore the effects of Xuanbai Chengqi decoction (XBCQD) combined with nutritional support on the nutritional status and gastrointestinal function of patients after colorectal cancer (CRC) surgery. Methods From January 2022 to January 2024, 128 CRC patients who visited our hospital were randomly assigned into the NS group and the XBCQD group. The 64 patients in the NS group received NS therapy, and 64 patients in the XBCQD group took XBCQD on the basis of NS therapy. The gastrointestinal function, gastrointestinal hormones, nutritional status, serum nutritional factors, lung function, immune function and complications were compared. Results The time of first exhaust, defecation time, eating time and recovery time of bowel sounds after surgery in the XBCQD group were all shorter than those in the NS group (P <0.05). After therapy, the levels of MTL and GAS in the XBCQD group were both higher than those in the NS group (P <0.05).The PG-SGA score of the XBCQD group was lower than that of the NS group, while the BMI, upper arm muscle circumference, levels of ALB, PA and TP of the XBCQD group were higher than those of the NS group (P <0.05). The levels of FEV1 and FVC in the XBCQD group were both higher than those in the NS group (P <0.05). The levels of NK cells, CD3+ and CD4+ in the XBCQD group were higher than those in the NS group, while the level of CD8+ was lower than that in the NS group (P <0.05). In addition, the complications were not prominent different between two groups (P >0.05). Conclusion The combined therapy of XBCQD and nutritional support in patients after CRC surgery can effectively promote the recovery of gastrointestinal function and nutritional status, and improve the immune function of patients.
