Analysis of traditional Chinese medicine syndrome distribution characteristics and clinical indicators in patients with acute calculous cholecystitis
CUI Zhi-gang,ZHENG Xin,SUN Yang
Abstract:
Objective To observe the distribution characteristics of Traditional Chinese Medicine (TCM) syndrome patterns in patients with acute calculous cholecystitis and to summarize the corresponding relationships between different syndromes and inflammatory indicators as well as ultrasonographic morphology. Methods A retrospective analysis was conducted on 109 patients with acute calculous cholecystitis treated at Tianjin Hospital of Integrated Traditional Chinese and Western Medicine from January 2024 to December 2025. Based on TCM four-diagnosis information and disease characteristics, the patients were classified into two main syndrome types: heat-toxin exuberance syndrome(n=12) and gallbladder fu depression-heat syndrome(n=97). Descriptive statistical methods were used to analyze the distribution features of each syndrome type, and differences between the groups in basic clinical data, total hospital stay, postoperative hospital stay, admission body temperature, white blood cell count (WBC), neutrophil percentage, C-reactive protein (CRP), gallbladder wall thickness, and gallbladder length were compared. Results Significant differences were found between patients with heat-toxin exuberance syndrome and those with gallbladder fu depression-heat syndrome in terms of age, comorbid diabetes, total hospital stay, postoperative hospital stay, admission body temperature, WBC, neutrophil percentage, and CRP levels(P <0.05). Conclusion Although the heat-toxin exuberance syndrome accounts for a smaller proportion, it is associated with the most severe condition. TCM syndrome types show correlations with inflammatory indicators and ultrasonographic morphological changes of the gallbladder, providing a basis for precise clinical assessment and guiding treatment decisions.
