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中药复方联合八段锦对老年骨质疏松性胸腰椎压缩骨折术后患者康复的疗效
施娟美,夏伟琴,朱跃明,王建东,陆吴超,张林强,钱琪群,钱伟宏
桐乡市中医医院骨伤科浙江桐乡 314500;桐乡市中医医院护理部浙江桐乡 314500;上海市第一人民医院骨科上海 200080
摘要:
目的:研究中药复方联合八段锦对老年骨质疏松性胸腰椎压缩骨折(OTCF)术后患者的疗效。方法:收集2023年2月—2024年2月在桐乡市中医医院就诊的OTCF患者120例,随机分为对照组、八段锦组、联合组,每组均40例。对照组术后予常规干预措施,八段锦组在对照组基础上同时采取八段锦康复训练,联合组在八段锦组基础上加用三期中药复方治疗。三组均治疗3个月。比较三组疼痛视觉模拟量表(VAS)评分、Oswestry功能障碍指数(ODI)评分、日常活动能力Barthel指数、Berg平衡量表(BBS)、Morse跌倒风险评估量表(MFS)评分、骨密度、骨折愈合时间、疗效、矢状位脊柱后凸Cobb角和伤椎前缘高度,以及血清骨保护素(OPG)和核因子κB受体活化因子配体(RANKL)水平。结果:治疗3个月后,三组疼痛VAS、ODI、MFS评分降低,Barthel指数、BBS评分增加,以联合组改善最明显(P <0.05)。三组腰椎正位(L2-4)、右跟骨的骨密度增加,以联合组改善最明显(P <0.05)。三组骨折愈合时间差异有统计学意义(P <0.05)。联合组总有效率高于八段锦组和对照组(P <0.05)。治疗后,三组矢状位脊柱后凸Cobb角减少,矢状位伤椎前缘高度增加,以联合组改善更明显(P <0.05)。治疗后,三组血清OPG水平增加,RANKL水平降低,以联合组改善更明显(P <0.05)。结论:三期中药复方联合八段锦对老年OTCF术后患者康复的疗效明显,能增加骨密度值,促进骨折愈合,并能调节血清OPG和RANKL水平。
关键词:  三期辨证  压缩性骨折  八段锦  骨质疏松  老年
DOI:10.3969/j.issn.1007-6948.2025.06.008
投稿时间:2025-03-20
基金项目:浙江省中医药科技计划项目(2023ZL717)
Efficacy of traditional Chinese medicine compound combined with Baduanjin on aged osteoporotic thoracolumbar compression fractures patients post operation
SHI Juan-mei,XIA Wei-qin,ZHU Yue-ming
Abstract:
Objective To study the efficacy of three periods syndrome differentiation of traditional Chinese medicine compound combined with Baduanjin on aged osteoporotic thoracolumbar compression fractures (OTCF) patients post operation. Methods A total of 120 OTCF patients treated in our hospital from February of 2023 to February of 2024 were randomly divided into control group, Baduanjin group, and joint group with 40 cases in each group. The control to the regular postoperative interventions. The Baduanjin group was treated with Baduanjin in addition to basic treatment. On the basis of the control group, joint group was given with three periods treatment of traditional Chinese medicine compound. All the three groups were observed for 3 months. The visual analogue scale (VAS) score, Oswestry disability index (ODI) score, Barthel index score of daily activities, Berg balance scale (BBS) and Morse fall scale (MFS) scores,bone mineral density, fracture healing time, treatment effect, sagittal kyphosis Cobb angle and the anterior edge of the injured vertebra, and serum levels of osteoprotegerin (OPG) and receptor activator of nuclear factor κB ligand (RANKL) were compared among the three groups. Results After treatment, scores of VAS, ODI, MFS for three groups were significantly decreased and the Barthel index and BBS score was evidently increased (P <0.05), and joint group improve the most significant (P <0.05). After treatment, bone mineral density of lumbar spine (L2-4), the right calcaneal of three groups of patients were evidently increased, and joint group improve the most significant (P <0.05). Three groups of fracture healing time difference were significant (P <0.05). After treatment, total effective rate of joint group was evidently higher than that of the Baduanjin group and control group (P <0.05). After treatment, the sagittal kyphosis Cobb angle of the patients in the three groups were evidently decreased, and the height of the anterior edge of the injured vertebra in the sagittal position was evidently increased, and the improvement in joint group was more obvious (P <0.05). After treatment, serum level of OPG of the three groups were evidently increased, and the RANKL level were evidently decreased (P <0.05), and the improvement in joint group was more obvious (P <0.05). Conclusion Three periods treatment of traditional Chinese medicine compound combined with Baduanjin on aged OTCF patients post operation has an evident efficacy, can increase BMD values, promote healing of fracture, and regulating serum levels of OPG and RANKL.
Key words:  Three periods syndrome differentiation  compression fracture  Baduanjin  osteoporosis  aged

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