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体外冲击波碎石术后应用石苇散加减治疗输尿管上段嵌顿性结石的疗效观察
赵元,王恒,徐维维
苏州市中医医院 泌尿外科江苏苏州 215000;苏州市中医医院 男性科江苏苏州 215000
摘要:
目的:分析输尿管上段结石嵌顿患者行超声引导下体外冲击波碎石术(ESWL)后应用石韦散加减治疗的疗效。方法:选取2021年5月—2024年10月在我院行经超声引导下ESWL的112例湿热蕴结证输尿管上段嵌顿性结石患者为研究对象,按照随机数字表法分为对照组与中药组,每组各56例,其中对照组术后给予常规治疗,中药组在对照组的基础上实施石韦散加减治疗,连续治疗14 d,对比两组结石排净率、血清白细胞计数(WBC)、C-反应蛋白(CRP)、降钙素原(PCT)、尿素氮(BUN)及血肌酐(Scr)水平,统计并比较两组不良反应发生情况。结果:中药组结石排净率为94.64%,高于对照组的82.14%,差异有统计学意义(P <0.05)。治疗14 d后,两组WBC、CRP、PCT、BUN、Scr水平较治疗前均下降,且中药组比对照组更低,差异有统计学意义(P <0.05)。中药组并发症总发生率(3.57%)较对照组(14.29%)更低,差异有统计学意义(P <0.05)。结论:湿热蕴结证输尿管上段嵌顿性结石患者于超声引导下ESWL术后应用石韦散加减汤治疗,临床效果明显,可降低炎症指标,改善肾功能,减少并发症的发生风险。
关键词:  输尿管上段嵌顿性结石  湿热蕴结证  体外冲击波碎石术  石韦散
DOI:10.3969/j.issn.1007-6948.2025.06.004
投稿时间:2025-09-18
基金项目:苏州市中西医结合科研基金项目(SKYD2023260)
Therapeutic effect of modified Shiwei Powder on incarcerated upper ureteral calculi after ultrasound-guided extracorporeal shock wave lithotripsy
ZHAO Yuan,WANG Heng,XU Wei-wei
Abstract:
Objective To analyze the therapeutic effect of modified Shiwei Powder on patients with incarcerated upper ureteral calculi after ultrasound-guided extracorporeal shock wave lithotripsy (ESWL). Methods 112 patients with incarcerated upper ureteral calculi of damp-heat accumulation syndrome who underwent ultrasound-guided ESWL in Suzhou Hospital of Traditional Chinese Medicine from May 2021 to October 2024 were enrolled in this study. They were assigned to the control group (n=56) and the traditional Chinese medicine group (n=56) according to the random number table method. The control group was given conventional postoperative treatment, while the traditional Chinese medicine group was treated with modified Shiwei Powder on the basis. Both groups were treated for 14 d. The stone clearance rate, white blood cell count (WBC), C-reactive protein (CRP), procalcitonin (PCT), urea nitrogen (BUN) and serum creatinine (Scr) levels were compared between the two groups. The incidence of adverse reactions and traditional Chinese medicine syndrome scores were statistically analyzed. Results The stone clearance rate in the traditional Chinese medicine group reached 94.64%, higher than that in the control group 82.14% (P <0.05). After 14 d of treatment, both groups showed reductions in WBC, CRP, PCT, BUN and Scr levels. These indexes in the traditional Chinese medicine group were lower compared with the control group (P <0.05). The total incidence of complications in the traditional Chinese medicine group was 3.57%, much lower than that in the control group 14.29% (P <0.05). Conclusion Applying modified Shiwei Powder to treat patients with incarcerated upper ureteral calculi after ultrasound-guided ESWL can significantly lower the levels of inflammatory indicators, improve renal function, and reduce the risk of complications.
Key words:  Incarcerated upper ureteral calculus  damp-heat accumulation syndrome  extracorporeal shock wave lithotripsy  Shiwei Powder

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