Risk factors analysis and prediction model construction of isolated distal deep vein thrombosis exacerbation during perioperative vascular surgery consultation
GUO Su-li,FAN Zi-yang,LIU Hong
Department of Vascular, Tianjin Union Medical Center, Tianjin300121，China
Abstract:
Objective To analyze the risk factors for exacerbation of isolated distal deep vein thrombosis (IDDVT) during perioperative consultation in vascular surgery and establish a prediction model. Methods A retrospective analysis was performed on 831 consultation medical records of the surgical group received by the Department of Vascular Surgery of Tianjin Union Medical Center from January 2021 to December 2021.A total of 563 cases were included. According to whether the extent of thrombosis was aggravated before and after the consultation, the patients were divided into aggravated group and non-aggravated group, including 61 cases of aggravated group and 502 cases of non-aggravated group. Lasso regression model and multiple Logistic regression were used to analyze the independent risk factors of IDDVT exacerbation during perioperative period of vascular surgical consultation. A prediction model was constructed with screened independent risk factors and a nomogram was drawn. Results The proportion of women with aggravated group, the proportion of bed time >72 h, BMI, WBC, GLO and PLT levels were higher than non-aggravated group, and the age, the proportion of coronary heart disease history and surgical history, ALB and HGB levels were lower than non-aggravated group, with statistical differences (P <0.05). In terms such as hypertension and D-dimer, FIB, there was no significant difference between the two groups. Multivariate Logistic regression analysis showed that, Gender being female, higher BMI, WBC and GLO, and bed time >72 h were independent risk factors for perioperative IDDVT exacerbation in vascular surgery consultations (P <0.05), and the area under ROC curve of the predictive model was 0.848. Conclusions Gender, BMI, WBC, GLO, and bed time >72 h are associated with perioperative isolated distal venous thrombosis exacerbation in vascular consultation. The prediction model constructed in this study is accurate and can provide individualized guidance for perioperative IDDVT patients in vascular consultation.
