Study of Qingre Lishi mixture combined with Huanglian Xiaozhong cream for the treatment of superficial vein thrombophlebitis of Shire Yuzu type
NIU Wen-jing,WANG Gang,WANG Jun
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin300381,China
Abstract:
Objective To evaluate the effectiveness of Qingre Lishi mixture combined with Huanglian Xiaozhong cream of superficial vein thrombophlebitis of Shire Yuzu type. Methods 100 patients admitted from the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from May 2023 to August 2024, A cohort study based on study protocol treatment as an exposure factor. The control group (non-exposed group) was treated with basic western medicine, In the observation group (exposure group), on the basic treatment of western medicine, Qingre Lishi mixture combined with Huanglian Xiaozhong cream. The treatment cycle was 10 days, Collection of general data, Investigate the TCM symptom score, clinical total response rate, and white blood cell number (WBC), C-reactive proteins(CRP), procalcitonin(PCT), D-dimer(DD), and coagulation markers, and pain NRS score. Results After 10 days of treatment, skin color, bar score, limb swelling and pain were lower than observation group (P ＜0.05); total response rate was 86.54% higher than control group; CRP and WBC lower (P ＜0.05), PCT was not statistically significant; APTT lower than control group (P ＜0.05); NRS score was (3.15±0.60) lower than observation group (3.44±0.31,P ＜0.05). Conclusion It is an effective method of Qingre Lishi mixture combined with Huanglian Xiaozhong cream for superficial vein thrombophlebitis of Shire Yuzu type.
