Clinical characteristics and risk factors of patients with acute cholecystitis combined with severe coronary artery lesions
ZHANG Ling,ZHU Wen-cheng,ZHANG Hong
Abstract:
Objective To explore the proportion, clinical characteristics and related risk factors of patients with acute cholecystitis combined with severe coronary lesions. Methods A total of 419 patients who were admitted to the Tianjin Hospital of ITCWM Hospital from January 2018 to June 2024 with a diagnosis of acute cholecystitis due to gallstones and planned for cholecystectomy, and who were highly suspected of coronary heart disease and underwent coronary angiography to assess surgical risk before surgery, were selected. According to the results of coronary angiography (CAG), patients were divided into two groups based on whether any of the three main branches of the coronary artery (anterior descending branch, circumflex branch, right coronary artery) had a stosis of more than 75%. The two groups were the non-severe coronary artery stenosis group (n=215) and the severe coronary stenosis group (n=204). The clinical characteristics of the two groups were observed, and the related risk factors were analyzed. Results The age, male proportion, history of type 2 diabetes, and Cr level were higher in the severe coronary artery lesion group than in the non-secoronary artery lesion group, and the body mass, TC, HDL, LDL, and EF were lower than in the non-severe coronary artery lesion group, statistically significant differences (P <0.05). Multivariate logistic regression analysis:Male, older age, and history of type 2 diabetes are the independent risk factors of severe coronary artery lesions in patients with acute cholecystitis. Small body mass and small left atrial anterior-posterior diameter are protective factors for severe coronary artery lesions patients with acute cholecystitis. Conclusions In patients with cholecystitis, male, old age, and a history of type 2 diabetes, attention should be paid to the presence of severe coronary lesions, and if necessary, appropriate treatment should be formulated according to the results of coronary angiography.
