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二甲硅油散和西甲硅油乳剂在胃镜检查前准备中的应用效果分析
陈艳
天津市南开医院天津 300100
摘要:
目的:比较二甲硅油散和西甲硅油乳剂在胃镜检查前准备中的应用效果。方法:选取2023年10月—12月在天津市南开医院内镜中心接受胃镜检查的患者共109例,按照随机数字表法分为三组,A组应用盐酸达克罗宁(n=38),B组应用二甲硅油散+盐酸达克罗宁(n=38),C组应用西甲硅油乳剂+盐酸达克罗宁(n=33),比较三组的胃镜下黏膜清晰度、微小病变检出率及不良反应发生情况。结果:盐酸达克罗宁胶浆联合应用二甲硅油散和西甲硅油乳剂可有效提高胃镜下黏膜清晰度和微小病变检出率,且盐酸达克罗宁胶浆联合应用西甲硅油乳剂改善胃镜下黏膜清晰度的效果优于盐酸达克罗宁胶浆联合二甲硅油散,差异有统计学意义(P <0.05),三组的不良反应发生率比较差异无统计学意义(P >0.05)。结论:在胃镜检查前准备中,盐酸达克罗宁胶浆联合应用西甲硅油乳剂效果更优,不仅可提高内镜检查视野清晰度,还可提高微小病变检出率,减少不良反应的发生,临床应用更为高效、安全。
关键词:  胃镜  术前辅助用药  盐酸达克罗宁  二甲硅油散  西甲硅油乳剂
DOI:10.3969/j.issn.1007-6948.2025.03.015
投稿时间:2024-05-06
基金项目:
Role of dimethicone powder and dimethicone emulsion in the preparation before gastroscopy
CHEN Yan
Tianjin Hospital of ITCWM Nankai Hospital, Tianjin300100, China
Abstract:
Objective To explore the role of dimethicone powder and simethicone emulsion in preparation before gastroscopy. Methods A total of 109 patients who underwent gastroscopy in the Endoscopy Center of Nankai Hospital from October 2023 to December 2023 were selected. The patients were divided into three groups according to the random number table method: dyclonine hydrochloride (n=38), simethicone powder+dyclonine hydrochloride (n=38) and simethicone powder+dyclonine hydrochloride (n=33). Results dyclonine mucilage hydrochloride combined with simethicone powder and simethicone emulsion can effectively improve the mucosal clarity and the detection rate of minor lesions under gastroscope, and the efficacy of combined application of simethicone emulsion in improving mucosal clarity under gastroscope is better than that of simethicone powder (P <0.05). There is no statistical difference in the occurrence of adverse reactions among the three groups(P >0.05). Conclusion In the preparation before gastroscopy, dyclonine mucilage combined with simethicone emulsion is more effective, which can not only improve the visual field of endoscopy, but also improve the detection rate of minor lesions, reduce the occurrence of adverse reactions, and the clinical application is more efficient and safe.
Key words:  Gastroscopy  preoperative adjuvant medication  dacronine hydrochloride  dimethicone powder  simethicone emulsion

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