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单侧双通道脊柱内镜技术治疗老年腰椎退行性疾病的效果观察
孙中政,王勇,孙凯,蒋泽辉
北大医疗鲁中医院脊柱外科山东淄博 245500
摘要:
目的 探讨单侧双通道脊柱内镜技术(UBE)治疗老年腰椎退行性疾病的临床效果。方法:选取2022年1月—2023年6月本院收治的老年腰椎退行性疾病患者80例,根据入院号奇偶数分为对照组和观察组,各组40例。对照组采取传统腰椎椎间融合术,观察组采取UBE治疗。比较两组治疗前后的视觉模拟评分(VAS)、腰椎日本骨科学会(JOA)评分、Oswestry功能障碍指数(ODI)评分、血清指标[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、IL-4],比较两组的临床效果、手术情况。结果:观察组临床有效率为97.50%,与对照组的87.50%相比差异无统计学意义(P>0.05)。观察组术后7 d、1个月、3个月的腰痛VAS、腿痛VAS分值低于对照组(P<0.05)。观察组术后7 d、1个月、3个月的JOA分值高于对照组,ODI分值低于对照组(P<0.05)。观察组术后7 d的TNF-α、IL-6水平低于对照组,IL-4水平高于对照组(P<0.05)。观察组术后并发症总发生率为5.00%,与对照组的12.50%相比差异不显著(P>0.05)。观察组的手术时间、术中出血量、术后住院时间均低于对照组(P<0.05)。结论:在老年腰椎退行性疾病中采取UBE治疗方案,能提高术后疼痛、腰椎功能、炎症反应改善效果,缩短手术时间、住院时间,减少术中出血量,疗效显著且有一定安全性。
关键词:  老年  腰椎退行性疾病  单侧双通道脊柱内镜技术  腰椎椎间融合术  临床效果
DOI:10.3969/j.issn.1007-6948.2025.02.013
投稿时间:2024-04-05
基金项目:2023年山东省淄博市医药卫生科研项目(20230407049)
Observation of the effect of unilateral two-channel spinal endoscopy in the treatment of degenerative diseases of the elderly lumbar spine
SUN Zhong-zheng,WANG Yong,SUN Kai
Department of Spinal Surgery, Lu Hospital of Traditional Chinese Medicine, Peking University Medical University, Zibo, Shandong 245500, China
Abstract:
Objective To investigate the clinical effect of unilateral dual-channel spinal endoscopy (UBE) in the treatment of degenerative diseases of the elderly lumbar spine. Methods A total of 80 elderly patients with lumbar degenerative diseases admitted to our hospital from January 2022 to June 2023 were selected and divided into control group and observation group according to the even admission number, with 40 cases in each group. The control group was treated with traditional lumbar interbody fusion, and the observation group was treated with UBE. Visual analogue scale (VAS), Lumbar Spine Japanese Orthopaedic Society (JOA) score, Oswestry Disability Index (ODI) score, serum indexes [TNF-α, interleukin-6 (IL-6), IL-4] before and after treatment were compared between the two groups, and the clinical effects and surgical conditions were compared between the two groups. Results The clinical effective rate of the observation group was 97.50%, with no statistically significant difference compared to the control group's 87.50% (P>0.05). The VAS scores of lumbago and leg pain in the observation group were lower than those in the control group at 7 days, 1 month and 3 months after operation (P<0.05). The JOA score of the observation group was higher than that of the control group at 7 days, 1 month and 3 months after surgery, and the ODI score was lower than that of the control group (P<0.05). The levels of TNF-α and IL-6 in the observation group were lower than those in the control group 7 days after surgery, while the level of IL-4 was higher than that in the control group (P<0.05). The total incidence of postoperative complications in the observation group was 5.00%, which was not significantly different from the control group's 12.50% (P>0.05). The surgical time, intraoperative blood loss, and postoperative hospital stay in the observation group were all lower than those in the control group (P<0.05). Conclusion In elderly patients with degenerative diseases of lumbar spine, UBE treatment can improve postoperative pain, lumbar function, inflammatory response, shorten operation time and hospital stay, and reduce intraoperative blood loss, with significant efficacy and certain safety.
Key words:  Old age  lumbar degenerative disease  unilateral two-channel spinal endoscopy  lumbar interbody fusion  clinical effect

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