Comparison of efficacy and safety of holmium laser enucleation of prostate and plasmakinetic resection of prostate in treating benign prostatic hyperplasia
LIU Zhen,YU Shi-cui,LUAN Jie
Abstract:
Objective To compare the therapeutic effect of holmium laser enucleation of the prostate (HoLEP) and plasmakinetic resection of prostate (PKRP) in the treatment of benign prostatic hyperplasia (BPH). Methods 138 patients with BPH in our hospital from January 2020 to January 2023 were prospectively selected and divided into HoLEP group and PKRP group by means of the random number table method, with 69 cases in each group. The perioperative related indicators, prostate symptoms, quality of life, urinary function, erectile function, ejaculatory function and occurrence of postoperative complications were compared. Results Compared with PKRP group, the surgical time in HoLEP group was longer, the intraoperative blood loss was less, the weight of resected gland was heavier, and the postoperative bladder irrigation time, urinary catheter indwelling time and hospital stay were shorter (P<0.05). At 3 months after surgery, the International Prostate Symptom Score (IPSS) and Quality of Life Index (QOL) score were lower in HoLEP group than those in PKRP group (P<0.05), and the maximum urinary flow rate (Qmax) and average urinary flow rate (Qave) were higher (P<0.05) and the residual urine volume (RUV) was less (P<0.05). The IIEF-5 score and ejaculatory function score of Male Sexual Health Questionnaire-Ejaculatory Dysfunction Scale (MSHQ-EjD) in HoLEP group were higher (P<0.05). The incidence rates of postoperative complications were comparable between HoLEP group and PKRP group (P>0.05). Conclusion Compared with PKRP, HoLEP has more advantages in the treatment of BPH, with smaller surgical trauma, better improvement of postoperative prostate symptoms and urinary function, and less impact on erectile function and ejaculatory function.
