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补肝健膝方对膝关节半月板损伤关节镜下成形术后康复的影响
林志坚,张伯佳,李红宝,杨凯,熊福生
川北医学院附属遂宁中医医院骨科遂宁 629000;普宁华侨医院中医科康复医学科普宁 515300
摘要:
目的 探究补肝健膝方对膝关节半月板损伤关节镜下成形术后康复效果及红细胞沉降率(ESR)、C反应蛋白(CRP)的影响。方法:选取2023年6月—2024年5月于川北医学院附属遂宁中医医院行膝关节半月板损伤关节镜下成形术的患者68例,采用简单随机抽样法将其随机分为研究组及对照组两组,,每组各34例。对照组患者采用常规功能锻炼,研究组患者在对照组患者基础之上添加补肝健膝方治疗。比较治疗前后两组患者中医症状积分、日本骨科协会评估治疗(JOA)评分、Lysholm膝关节评分、血清炎症指标[ESR、CRP、白细胞计数(WBC)、白细胞介素-17(IL-17)]、血清氧化应激指标[丙二醛(MDA)、超氧化物歧化酶(SOD)]。结果:治疗后,两组患者中医症状积分及ESR、CRP、WBC、IL-17、MDA水平均降低,JOA评分、Lysholm膝关节评分及SOD水平上升,且研究组患者中医症状积分及ESR、CRP、WBC、IL-17、MDA水平较对照组更低,JOA评分、Lysholm膝关节评分及SOD水平更高(P<0.05)。结论:补肝健膝方能改善膝关节半月板损伤关节镜下成形术后的膝关节功能康复效果,缓解临床症状,且有助于减轻炎症反应和氧化应激状态。
关键词:  补肝健膝方  膝关节  半月板损伤关节镜下成形术  康复效果  关节功能
DOI:10.3969/j.issn.1007-6948.2025.02.010
投稿时间:2024-12-22
基金项目:四川省中医药管理局科学技术研究专项课题(2024MS346)
Influence of Bugan Jianxi decoction on rehabilitation after arthroscopic plasty for knee meniscus injury
LIN Zhi-jian,ZHANG Bo-jia,LI Hong-bao
Department of Orthopedics, Suining Hospital of Traditional Chinese Medicine Affiliated to North Sichuan Medical College, Suining, Sichuan (629000), China
Abstract:
Objective To explore the influence of Bugan Jianxi decoction on the rehabilitation effect, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) after arthroscopic plasty for knee meniscus injury. Methods From June 2023 to May 2024, 68 patients with knee meniscus injury who received arthroscopic plasty in Suining Hospital of TCM Affiliated to North Sichuan Medical College were selected and randomized into study group and control group by simple randomization method, with 34 cases in each group. The patients in the control group were treated with routine functional exercise, while the patients in the study group were added with Bugan Jianxi decoction on the basis of the control group. The scores of TCM symptoms, Japanese Orthopedic Association (JOA) score, Lysholm knee score, serum inflammatory indexes [ESR, CRP, white blood cell count (WBC), interleukin-17 (IL-17)] and serum oxidative stress indexes [malondialdehyde (MDA), superoxide dismutase (SOD)] were counted in both groups before and after treatment. Results After treatment, both groups exhibited decreased scores of TCM symptoms, reduced levels of ESR, CRP, WBC, IL-17 and MDA and increased JOA score, Lysholm knee score and SOD level. Compared to the control group, the study group showed lower TCM symptoms, ESR, CRP, WBC, IL-17 and MDA, and higher JOA score, Lysholm knee score and SOD level (P<0.05). Conclusion Bugan Jianxi decoction can improve the rehabilitation effect of knee function after arthroscopic plasty for knee meniscus injury, relieve the clinical symptoms, and help to relieve the inflammatory response and oxidative stress status.
Key words:  Bugan Jianxi decoction  knee joint  arthroscopic meniscus injury plasty  rehabilitation effect  joint function

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