The value of T2WI-fat-suppression sequence in diagnosis acute pancreatitis-associated liver injury
LI Si-cong,GONG Yan,ZHANG Xiang
Department of Radiology, Tianjin Nankai Hospital, TianJin300100,China
Abstract:
Objective To evaluate the diagnostic value of magnetic resonance imaging (MRI) T2WI-fat-suppression sequence for acute pancreatitis-associated liver injury. Methods A retrospective analysis was performed on 134 patients with acute pancreatitis who underwent MRI examination for the first time in Tianjin Nankai Hospital from January 2019 to January 2023. According to laboratory information of liver function, including ALT alanine aminotransferase (ALT), total bilirubin (TBIL), and albumin (ALB), the enrolled patients were divided into liver function injury group(n=90) and liver function normal group(n=44). The abdominal MRI imaging signs of all patients were analyzed, and the frequency of liver edema, periportal oedema and gallbladder wall edema was recorded. The independent and combined receiver operating characteristic (ROC) curves of three signs were drawn based on biochemical examination as the golden standard according to grouping. By comparing the area under the ROC curve (AUC), the diagnostic value of the three MRI signs(liver edema, periportal lymphedema, and gallbladder wall edema) for acute pancreatitis-associated liver function injury was elucidated. Results Liver function injury group's inflammatory index amylase and C-reflection protein were significantly higher than liver function normal group(P <0.05). The interobserver and intraobserver agreement of liver edema, periportal lymphedema, and gallbladder wall edema were high in diagnosing pancreatitis-associated liver injury(κ＞0.8). The AUC values of liver edema, periportal lymphedema, and gallbladder wall edema in diagnosing pancreatitis-associated liver injury were 0.67, 0.65, 0.67, respectively, their sensitivity were 0.41, 0.34, 0.39, specificity were 0.93, 0.95, 0.95. The AUC, sensitivity for the liver edema+ periportal lymphedema+gallbladder wall edema combined diagnosis of pancreatitis-associated liver injury were improved to 0.82, the sensitivity were 0.76,and the specificity were 0.89. Conclusion T2WI-fat-suppression sequence can be used as an effective means to evaluate whether patients with acute pancreatitis are complicated with liver injury. Combined MRI features of liver edema, periportal oedema, and gallbladder wall edema can improved the diagnostic efficiency and provide prevention and treatment basis for patients with acute pancreatitis-associated liver injury.
