Clinical observation of Bushen Tongluo decoction combined with Xianling Gubao capsule in the treatment of senile osteoporotic distal radius fracture
LUO Jie,YUAN Shang-feng,PENG Zhen-ling
Department of Orthopaedics, Zhuzhou Traumatology Hospital, Zhuzhou, Hunan(412000),China
Abstract:
Objective To investigate the clinical effect of Bushen Tongluo decoction combined with Xianling Gubao capsule on osteoporotic distal radius fracture. Methods A total of 124 patients with osteoporotic distal radius fracture were selected from our hospital and divided into the observation group and the control group with 62 patients in each group according to the method of random number table. Control group was given conventional western medicine treatment, observation group was given Bushen Tongluo decoction combined with Xianling Gubao capsule on the basis of control group. To observe the clinical efficacy, TCM syndrome scores, fracture healing time, swelling subside time and pain relief time of the two groups were observed before and after treatment. Serum bone metabolic indices (serum osteocalcin, amino terminal propeptide of type I procollagen, C-terminal peptide β degradation products of type I collagen), bone density level, wrist joint function and complications. Results After treatment, the observation group total effective rate was 94.92% significantly higher than that of control group 84.75%(P <0.05). TCM syndrome score and serum level of C-terminal peptide β degradation product of type Ⅰ collagen in 2 groups were lower than before treatment, and observation group was lower than control group (P <0.05). After treatment, fracture healing time, swelling regression time and pain relief time in observation group were shorter than those in control group (P <0.05). After treatment, serum osteocalcin, amino terminal propeptide of serum type I procollagen, bone mineral density, palm inclination angle and ulnar declination angle in 2 groups were increased compared with before treatment, and observation group was higher than control group (P <0.05). After treatment, the complication rate of observation group was 6.78%, which was significantly lower than that of control group (20.34%) (P <0.05). Conclusion Bushen Tongluo decoction combined with Xianling Gubao capsule has significant clinical effect on senile osteoporotic distal radius fracture.
