Influencing factors of postoperative recurrence and metastasis in patients with non-small cell lung cancer undergoing minimally invasive thoracoscopic resection
CHEN Jian，MENG Jing-jing，ZHAO Yong-sheng
Abstract:
Objective To investigate the factors influencing the recurrence and metastasis of 90 patients with non-small cell lung cancer (NSCLC) who underwent minimally invasive thoracoscopic resection. Methods The clinical data of 90 NSCLC patients admitted to our hospital from June 2019 to May 2022 for minimally invasive thoracoscopic resection were selected. The postoperative recurrence and metastasis of 90 patients were recorded, and risk factors influencing the postoperative recurrence and metastasis of NSCLC patients were analyzed. Results The follow-up time was up to September 2022, ranging from 5 to 32 months (18.22 ± 5.68). Among 90 patients, 32 patients had recurrence (35.56%) and 35 patients had metastasis (38.04%). Logistic regression analysis showed that pathological stage, N stage, T stage, degree of differentiation, mediastinal lymph node metastasis, positive resection of trachea stump were independent risk factors affecting postoperative recurrence of NSCLC patients. Pathological stage, N stage, T stage, degree of differentiation, mediastinal lymph node metastasis, number of lymph node metastasis, positive resection of trachea stump and were independent risk factors affecting postoperative metastasis of NSCLC patients. postoperative chemotherapy was the protective factors of NSCLC patient. Conclusion Pathological stage, degree of differentiation, mediastinal lymph node metastasis, positive resection of trachea stump and postoperative chemotherapy are the common risk factors for postoperative recurrence and metastasis of NSCLC patients. The number of lymph node metastasis is an independent risk factor for postoperative metastasis. The above factors should be fully considered in clinical treatment.
