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经括约肌间入路TROPIS改良挂线法治疗高位肛瘘的临床效果
王燕,侯毅,郑雪平,姜韵琳,吕奕,马雅景
南京中医药大学南京 210000;南京中医药大学附属南京中医院肛肠中心南京 210000
摘要:
目的 研究TROPIS改良挂线法治疗高位肛瘘的临床疗效。方法:将72例高位肛瘘患者随机分为治疗组(采用TROPIS改良挂线法治疗,n=36)和对照组(采用切开挂线术治疗,n=36),比较两组的疼痛指数、创面面积(术后当天、术后14 d、术后1个月)、肛管静息压(ARP)、肛管最大收缩压(AMCP)、大便失禁Wexner评分、创面愈合时间、住院时间、住院费用、术后并发症及复发情况。结果:两组患者的住院时间、治愈率、肛管静息压、肛管最大收缩压比较差异无统计学意义(P>0.05)。治疗组的创面愈合时间[60(50,79)]d,短于对照组的[110(96, 129)]d;治疗组住院费用为(11 134.53±3 394.88)元,少于对照组的(14 225.92±6 535.61)元;治疗组使用镇痛泵组的疼痛指数为[1.0(0.0, 1.0)]分,低于对照组的[2.0(1.0,2.0)]分;治疗组术后当天、术后14 d、术后1个月的创面面积分别为(10.58±5.62)cm2、(6.59±4.24)cm2、(3.56±3.03)cm2,均小于对照组的(28.05±5.76)cm2、(21.59±4.49)cm2、(13.48±3.63)cm2,随着治疗时间延长,治疗组的创面面积缩小幅度更大;治疗组术后3月大便失禁评分为[0.0(0.0,1.0)]分,低于对照组的[2.0(0.0,2.0)]分;术后漏气漏液的发生率为2.8%(1/35),少于对照组的16.7%(6/30),差异有统计学意义(P<0.05)。结论:与切开挂线术相比,TROPIS改良挂线法治疗高位肛瘘治愈率高,肛门括约功能损伤小,安全有效,并发症少,具有经济效益,值得临床推广。
关键词:  高位肛瘘  保留括约肌术式  经括约肌间入路  括约肌间感染机制
DOI:10.3969/j.issn.1007-6948.2023.02.005
基金项目:南京市卫生科技发展专项资金项目(YKK21197);南京市卫生科技发展专项资金项目(YKK22175);2022年江苏省研究生实践创新计划(SJCX22_0819);南京市“十三五 ”规划名中医工作2,室建设项目(ZXP-2019-NJ)
Clinical observation of transsphincteric TROPIS modified suture method in treatment of high anal fistula
WANG Yan,HOU Yi,ZHENG Xue-ping
Nanjing University of Traditional Chinese Medicine, Nanjing (210000), China
Abstract:
Objective To study the clinical effect of TROPIS modified suture method in the treatment of high anal fistula. Methods Seventy-two patients with high anal fistula were randomly divided into experimental group (TROPIS modified suture method, n=36) and control group (incision suture method, n=36). The pain index, wound area (postoperative day, postoperative 14 days, postoperative 1 month), anal canal resting pressure (ARP), anal canal maximum systolic pressure (AMCP), Wexner score of fecal incontinence, wound healing time, length of stay, hospitalization cost, postoperative complications and recurrence were compared between the two groups. Results There were no significant differences in hospital stay, cure rate, anal canal resting pressure and anal canal maximum systolic pressure between two groups (P > 0.05). The wound healing time in the treatment group [60 (50,79)]d was shorter than that in the control group [110 (96, 129)]d. The hospitalization cost of the treatment group was (11 134.53±3 394.88) yuan, which was less than that of the control group (14 225.92±6 535.61) yuan. The pain index in the treatment group was [1.0 (0.0, 1.0)], lower than that in the control group [2.0 (1.0, 2.0)]. The wound area of the treatment group was (10.58±5.62)cm2, (6.59±4.24)cm2 and (3.56±3.03)cm2 on the day after surgery, 14 days after surgery and 1 month after surgery respectively, which were all smaller than those in the control group (28.05±5.76)cm2, (21.59±4.49)cm2 and (13.48±3.63)cm2. With the extension of treatment time, the reduction of wound area in the treatment group was larger. The score of fecal incontinence 3 months after operation in the treatment group was [0.0 (0.0,1.0)], which was lower than that in the control group [2.0 (0.0, 2.0)]. The probability of postoperative complications of air leakage and fluid leakage was 2.8%(1/35) less than that of control group 16.7% (6/30) (all P < 0.05). Conclusion Compared with incision and transfixion, TROPIS modified suture method for the treatment of high anal fistula has a higher cure rate, less damage to the anal pericardial function, safety and effectiveness, less complications, economic benefits, and it is worthy of clinical promotion.
Key words:  High anal fistula  sphincter sparing operation  transsphincteric approach  intersphincter infection mechanism

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