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舒筋壮骨汤结合经皮椎体成形术治疗骨质疏松压缩性脊柱骨折对患者腰椎功能和骨代谢水平的影响
殷浩,余利军,方婷婷
浙江省淳安县中医院骨伤科杭州 311700
摘要:
目的:观察舒筋壮骨汤结合经皮椎体成形术(PVP)治疗骨质疏松压缩性脊柱骨折对患者腰椎功能和骨代谢水平的影响。方法:选取我院2018年8月—2020年8月收治的骨质疏松压缩性脊柱骨折患者114例,根据入院顺序采用随机数字法分为两组,每组57例。对照组给予PVP治疗,观察组给予舒筋壮骨汤结合PVP治疗。统计两组总有效率,应用视觉模拟(VAS)评分法和Oswestry功能障碍指数(ODI)评价疼痛程度和腰椎功能障碍程度,检测两组骨代谢相关因子及腰椎骨密度(BMD)的变化,随访6个月,记录并比较两组邻近椎体骨折再发生率。结果:观察组临床痊愈24例,显效和有效共29例,总有效率92.98%,高于对照组(78.95%),差异有统计学意义(P<0.05)。与治疗前比较,两组治疗2周、12周后VAS评分、ODI评分下降(P<0.05),观察组治疗2周、12周后VAS评分、ODI评分低于对照组(P<0.05)。与治疗前比较,两组治疗2周、12周后血钙、骨钙素升高(P<0.05),骨碱性磷酸酶下降(P<0.05),观察组治疗2周、12周后血钙、骨钙素高于对照组(P<0.05),骨碱性磷酸酶低于对照组(P<0.05)。与治疗前比较,两组治疗2周、12周后腰椎BMD升高(P<0.05),观察组治疗2周、12周后腰椎BMD高于对照组(P<0.05)。随访6个月,观察组邻近椎体骨折再发生率3.51%,低于对照组的15.79%,差异有统计学意义(P<0.05)。结论:舒筋壮骨汤结合PVP治疗骨质疏松压缩性脊柱骨折可改善骨代谢,提高骨密度,减轻疼痛,改善腰椎功能。
关键词:  舒筋壮骨汤  经皮椎体成形术  骨质疏松压缩性脊柱骨折  腰椎功能  骨代谢
DOI:10.3969/j.issn.1007-6948.2023.01.010
基金项目:浙江省青年人才基金项目(2021ZQ080)
Effect of Shujin Zhuanggu decoction combined with PVP on lumbar function and bone metabolism in patients with osteoporotic vertebral compression fractures
YIN Hao,YU Li-jun,FANG Tingting
Department of Orthopedics and Traumatology, Chun' an Hospital of Traditional Chinese Medicine, Hangzhou 311700, China
Abstract:
Objective To observe the effect of Shujin Zhuanggu decoction combined with percutaneous vertebroplasty (PVP) on lumbar spine function and bone metabolism in patients with osteoporotic compression spinal fractures. Methods A total of 114 patients with osteoporotic vertebral compression fractures who were admitted to our hospital from August 2018 to August 2020 were selected and randomly divided into two groups according to the order of admission, with 57 cases in a single group. The control group was given PVP treatment, and the observation group was given Shujin Zhuanggu decoction combined with PVP treatment. The total effective rate of the two groups was counted, the visual analogue scale (VAS) score and the Oswestry disability index (ODI) were used to evaluate the degree of pain and lumbar spine dysfunction, and the changes of bone metabolism-related factors and lumbar spine bone mineral density (BMD) were detected in the two groups. During the 6-month follow-up, the recurrence rates of adjacent vertebral fractures in the two groups were recorded. Results In the observation group, 24 cases were clinically cured, 29 cases were markedly effective and efficacious, and the total effective rate was 92.98%, which was higher than that in the control group(78.95%) and the
Key words:  Shujin Zhuanggu decoction  percutaneous vertebroplasty  osteoporotic compression fractures of the spine  lumbar spine function  bone metabolism

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