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结肠镜下单纯性直肠溃疡的临床特征分析
赵狄,刘艳迪
天津市人民医院消化内科天津 300122
摘要:
目的:分析结肠镜发现的单纯性直肠溃疡的临床特征及病理特点。方法:回顾性分析2016 年9 月—2022 年3 月在天津市人民医院消化内科进行结肠镜检查的37 489 例患者的临床资料。入选标准:直肠溃疡,直径≥ 0.2 cm,单发或多发,无结肠炎及结肠溃疡等其他结直肠疾病。入选患者44 例,占同期行结肠镜检查者的1.17‰(44/37 489)。其中男性21例,女性23 例,年龄16~81 岁,平均(53.0±14.8)岁。结果:44 例单纯性直肠溃疡的症状包括便血、腹痛、排便不尽感、下腹/ 肛门坠胀、腹泻、腹胀及排便次数增多等,还有个别患者出现排便费力、里急后重及发热等表现。其中以腹痛及便血最为常见,占比达40% 以上。内镜表现:溃疡直径0.2~1.0 cm 者24 例,1.1~3.0 cm 者13 例,> 3.0 cm 者7 例。单发溃疡25 例(56.8%),多发溃疡12 例(27.3%),占据管腔1/4 及以上大溃疡7 例(15.9%)。病因学分析:非特异性直肠炎29 例,溃疡性直肠炎5 例,缺血性直肠炎4 例,肠克罗恩病、肠阿米巴病各1 例,还有4 例未明确病因,其中病理可见异型细胞3 例,疑似血管炎相关疾病1 例。结论:非特异性直肠炎在单纯性直肠溃疡中所占比例较高。内镜联合活检对于明确单纯性直肠溃疡的病因具有重要意义。
关键词:  直肠溃疡  结肠镜检查  病因学
DOI:10.3969/j.issn.1007-6948.2022.00.020
投稿时间:2022-06-18
基金项目:
Clinical features of simple rectal ulcer discovered by colonoscopy
ZHAO Di,LIU Yandi
Department of Gastroenterology, Tianjin People' s Hospital, Tianjin 300122, China
Abstract:
Objective To investigate the clinical and pathological features of the simple rectal ulcer proven by colonoscopy. Methods The clinical data of 44 patients, accounted for 1.17‰(44/37 489) of the patients who underwent colonoscopy during the same period,21 males and 23 females, aged (16-81) (53.0±14.8) with simple rectal ulcers value, ≥ 2 mm in diameter, excepting colitis, colonic ulcer and other colorectal diseases were analyzed in Tianjin People' s Hospital from September 2016 to March 2022. Results The clinical manifestations included hematochezia, abdominal pain, sensation of incomplete defecation, lower abdominal/ perianal distension, diarrhea, abdominal distension and increased stool frequency. Less frequent symptoms include defecatory straining, tenesmus and fever. Abdominal pain and hematochezia were the most common symptoms accounted for more than 40%. 24 patients had the ulcers 0.2~1.0 cm in diameter, 13 patients with the size of 1.1~3.0 cm and 7 patients were larger than 3.0 cm. Single ulcer was seen in 25 patients(56.8%)and multiple in 12(27.3%), there were 7 patients(15.9%)with the ulcers more than a quarter of the intestinal canal. Mostly, 29 cases were diagnosed as non-specific proctitis. The other diagnoses were ulcerative proctitis (5 cases), ischemic proctitis (4 cases), Crohn' s disease (1 case) and amebic colitis (1 case). In addition,there were 4 cases with unknown etiology, including 3 cases with pathological atypia, and 1 case with vasculitisrelated diseases. Conclusion Non-specific proctitis is a high proportion in the spectrum of simple rectal ulcer.Colonoscopy plus biopsy play an important role in the etiological diagnosis of simple rectal ulcer.
Key words:  Rectal ulcer  colonoscopy  etiology

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