Systematic Evaluation of Yiqi Tongfu Method on Recovery of Gastrointestinal Function after Colorectal Cancer Surgery
ZHANG Xin-yi,CAO Li-xing
The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
Abstract:
Objective To evaluate the effect of Yiqi Tongfu method on the recovery of gastrointestinal function after colorectal cancer operation. Methods The relevant literature from the establishment of the database to September 1st, 2021 was searched in five databases: China Knowledge Network (CNKI), Wanfang,VIP database, China biomedical literature database (CBM) and PubMed. Two researchers independently screened the literature and extracted the data. The quality of the included studies were evaluated using the Cochrane risk bias assessment tool, and Meta-analysis was performed using RevMan 5.3. Results A total of 40 literature involving 3 486 subjects were included in the study, and the quality of the literature was generally low. Meta analysis showed that Yiqi Tongfu method could shorten the first exhaust time after colorectal cancer [MD=-12.17, 95%CI (-14.11, -10.24), P <0.001], the first defecation time [MD=-15.41, 95%CI (-18.06, -12.76), P <0.001],the recovery time of bowel sounds [MD=-10.16, 95%CI (-12.90, -7.42), P <0.001], and reduce the incidence of adverse reactions like postoperative nausea, vomiting and abdominal distension [OR=0.30, 95%CI (0.21,0.42), P <0.001]. Conclusion The method of Supplementing Yiqi Tongfu medicine can promote the recovery of gastrointestinal function after colorectal cancer surgery, but there is few literature and the quality is low. The conclusions still have yet to be verified by high-quality research.
