Incidence and Risk Factors of Sessile Serrated Adenoma after Radical Resection of Left Colorectal Cancer
DONG Tian-zeng，ZHANG Li-rong
Abstract:
Objective To investigate the incidence and risk factors of sessile serrated adenoma (SSA)after radical resection of left colorectal cancer. Methods 270 patients with left colon cancer and rectal cancer treated in our hospital from September 2011 to September 2016 were analyzed retrospectively. At least 2 colonoscopic follow-up were carried out after operation. The baseline characteristics, SSA pathological data and colonoscopy information were collected. Results The average follow-up time of the first colonoscopy was 11.5 months and that of the second was 25.8 months. At the first follow-up, 48 SSAs were found in 59 patients (21.8%). At the second follow-up, 40 SSAs were found in 63 patients (23.3%). Among 88 SSAs, 49 cases showed flat and 31 cases showed hemispherical eminence. The diameter ranged from 2.8mm to 40.0mm, of which 61 cases were less than 5mm, 19 cases were 5~10mm and 8 cases were more than 10mm. The BMI, alcohol consumption, TNM stage and degree of differentiation were independent risk factors for SSA during the first postoperative colonoscopy. Conclusion The incidence of sessile serrated adenoma after radical resection of left colorectal cancer is high, especially in patients with obesity, alcohol consumption, TNM stage III and low tumor differentiation.
