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中药穴位热敷治疗胃癌腹膜转移患者术后胃肠功能紊乱的临床研究
何佩珊,姜敏,杨公博,潘国凤,李雁,安松林,姬忠贺
首都医科大学附属北京世纪坛医院中医科北京 100038;中国中医科学院西苑医院创伤科北京 100091;首都医科大学附属北京世纪坛医院腹膜外科 北京100038
摘要:
目的:研究中药小茴香穴位热敷治疗胃癌腹膜转移患者接受肿瘤细胞减灭术后出现胃肠功能紊乱的临床疗效。方法:收集2020 年4 月—2020 年9 月期间接受肿瘤细胞减灭术的胃癌腹膜转移患者65 例,临床分期均为Ⅳ期,分为中药热敷组34 例(术后中药热敷治疗+ 围手术期常规治疗)和对照治疗组31 例(术后仅予围手术期常规治疗),比较两组首次自主排便时间、气虚证主要症状评分以及营养状态评分。结果:首次自主排便时间:经治疗后,中药热敷组首次自主排便时间为(7.19±1.52)d,比对照治疗组(8.41±1.96)d 短,差异具有统计学意义(P =0.007)。主要症状评分比较:术后7 d,中药热敷组体倦乏力症状评分比对照治疗组低,差异具有统计学意义(P =0.031)。术后14 d,两组的症状评分较术后7 d 均有所下降,中药热敷组恶心呕吐、腹胀腹痛、体倦乏力3 项症状评分和总积分均比对照治疗组低,差异具有统计学意义(P < 0.05)。营养状态评分比较:术后7 d,两组营养状态评分差异无统计学意义;术后14 d,中药热敷组营养状态评分(9.95±2.39)比对照治疗组(7.91±2.71)高,差异具有统计学意义(P =0.001)。结论:中药穴位热敷可以促进胃癌腹膜转移患者术后排便功能恢复,缓解恶心呕吐、腹胀腹痛、体倦乏力等气虚证症状,并有利于改善患者营养状态,具有积极的临床意义。
关键词:  胃癌腹膜转移  中药热敷  胃肠功能紊乱
DOI:10.3969/j.issn.1007-6948.2022.06.011
投稿时间:2022-01-02
基金项目:北京市中医药科技发展基金项目(JJ-2020-58);北京市属医院科研培育计划项目(PZ2021009);中医药循证能力建设项目(2019XZZX-JB004);北京市科技新星计划项目(141107001814061);北京市卫生系统高层次卫生技术人才培养计划(2014-3-046);北京市科委首都临床特色应用研究项目(z181100001718150);北京市中西医结合肿瘤研究所建设项目
Observation on Acupuncture Point Hot Compress of Chinese Medicine Treating Gastrointestinal Dysfunction on Gastric Cancer Peritoneal Metastasis Patients after Cyto-Reductive Surgery
HE Pei-shan,JIANG Min,YANG Gong-bo
Abstract:
Objective To observe the clinical effect of acupuncture point hot compress of chinese medicine treating gastrointestinal dysfunction on gastric cancer peritoneal metastasis patients after cyto-reductive surgery. Methods Total 65 gastric cancer peritoneal metastasis patients with gastrointestinal dysfunction after cytoreductive surgery were divided into 2 groups. Group I including 34 patients were given the treatments of acupuncture point hot compress of chinese medicine and perioperative therapy. Group II including 31 patients were given the treatments of perioperative therapy only. First defecating time, main symptom score of qi deficiency and nutrition assessment score were observed and analyzed. Results First defecating time: The first defecating time of group I was (7.19±1.52)d, which lower than those (8.41±1.96)d of group II (P=0.007). Main symptom score of qi deficiency: The fatigue symptom score of group I was lower than those of group II 7 days after cyto-reductive surgery (P =0.031). The symptom score of nausea and vomit, bloating and abdominal pain, fatigue, and total scores of group I were lower than those of group II 14 days after surgery (P < 0.05).Nutrition assessment score: The nutrition assessment score of group I (9.95±2.39) were higher than group II(P =0.001). Conclusion Acupuncture point hot compress of chinese medicine could help gastric cancer peritoneal metastasis patients shorten the first defecating time after cyto-reductive surgery,relieving symptoms of nausea and vomit, bloating and abdominal pain, and fatigue, improving nutritional status.
Key words:  Gastric cancer peritoneal metastasis patients  external application of chinese medicine  gastrointestinal dysfunction

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