Department of General Surgery,Affiliated Traditional Chinese Medicine Hospital of Nantong University, Nantong Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nantong 226001, China
Abstract:
Objective To observe the clinical efficacy of the treatment from liver and stomach simultaneously combined with hormone in the treatment of non-puerperal mastitis patients in acute tumor stage. Methods 90 patients with non-puerperal mastitis in acute tumor stage were selected and divided into groups A, B and C according to the random number table, which 31 cases in group A, 29 cases in group B, and 30 cases in group C. Group A was given oral prednisone acetate and Shugan Sanjie decoction, group B was given oral prednisone acetate, and group C was given oral Shugan Sanjie decoction, all of which were treated for 8 weeks. The clinical symptoms and signs scores (tumor size, skin color, skin temperature, pain), total effective rate, inflammatory factors (WBC, CRP, IL-6, IL-2, IL-4) and immunoglobulin (IgA, IgM, IgG) were observed.Results There was no significant difference in the scores of clinical symptoms and signs, inflammation indexes and immune indexes in three groups before treatment (P >0.05), and all indexes in three groups significantly reduced after treatment (P <0.05). The indexes in group A were lower than those in group B after treatment (P >0.05),and the tumor size is equivalent to that of group C (P >0.05). The other indicators are lower than those of group C (P <0.05), and the tumor size of group B is higher than that of group C. The rest of the indicators are lower than those of group C (P <0.05), and the total effective rate is equivalent to that of group C(P >0.05). Adverse reactions in group A were similar to group B (P>0.05), and higher than group C (P<0.05). Conclusion The treatment from liver and stomach simultaneously combined with hormone can effectively reduce the tumor of patients with non-puerperal mastitis, control in.ammation and regulate autoimmunity. The clinical effect is signi.cant, safe and effective.
