Effect of Invigorating Spleen and Nourishing Kidney Prescription, Biofeedback Combined with Pelvic Floor Muscle Function Training on Stress Urinary Incontinence in Elderly Women
WU Chao-xia，XU Xin，XU Hai
Abstract:
Objective To observe the effect of invigorating spleen and nourishing kidney prescription, biofeedback combined with pelvic floor muscle function training in the treatment of stress urinary incontinence in elderly women. Methods 126 elderly female patients with stress urinary incontinence were randomly divided into control group and observation group. The control group was given pelvic floor muscle function training, and the observation group was given spleen and kidney strengthening prescription combined with pelvic floor biofeedback internal and external treatment on the basis of the control group. Urodynamics related parameters, 1h urine leakage, 24h urine leakage frequency, ICI-Q-SF score, pelvic floor muscle potential and urinary incontinence quality of life scale (I-QOL) score were compared between the two groups. The levels of transforming growth factor-β1 (TGF-β1) and 25 hydroxyvitamin D (25-OHD) in serum were monitored. Results Compared with the control group (70.00%), the effective rate of the observation group (95.00%) was significantly increased (P<0.05). Compared with the control group, the parameters related to urodynamics in the observation group after treatment were significantly increased (t=6.174，-5 . 317，-5.311，-6.801，-2.835，-2.515，P< 0 . 05 ). The amount of urinary incontinence at 1h was significantly decreased, and the frequency of urinary incontinence at 24 h was significantly decreased (t=14.042, 7.287, P<0.05). After 4 and 8 weeks of treatment, the ICI-Q-SF scores in the observation group were signi.cantly lower than those in the control group (t=7.830, 28.852, P<0.05). After treatment, the pelvic floor muscle potential (65.32±7.19) μV of the observation group was significantly higher than that of the control group (54.25±5.36) μV (t=9.401, P<0.05). After 4 and 8 weeks of treatment, the I-QOL score of the observation group was signi.cantly higher than the control group, which the difference was statistically signi.cant (t=3.999, 7.033, P<0.05). Compared with the control group, the contents of TGF-β1 and 25-OHD related to the proliferation of pelvic floor myofibroblasts in serum of the observation group were significantly increased after treatment (t=-5.360, -5.187, P<0.05). Conclusion The spleen and kidney strengthening prescription, biofeedback combined with pelvic .oor muscle function training can reduce the urinary incontinence symptoms of elderly female patients with stress urinary incontinence, improve the quality of life, improve the parameters of urodynamics, increase the serum TGF-β1, 25-OHD content to enhance pelvic .oor muscle strength, which is worthy of promotion.
