Effect of Laser Combined with Botulinum Toxin Type A for the Treatment of Scar Hyperplasia after Acute Appendectomy
JI Yi-fa，ZHOU Ya-jing，LIU yi
Abstract:
Objective To explore whether the use of 595 nm pulsed dye laser combined with botulinum toxin type A could reduce the wound scar hyperplasia after actue appendectomy. Methods 100 patients who underwent appendectomy in our hospital from May 2020 to December 2020 were randomly divided into botulinum toxin group and pulsed dye laser+botulinum toxin group. The botulinum toxin group was combined with the use of botulinum toxin A during routine suture. The pulsed dye laser+botulinum toxin group was combined with the use of pulsed dye laser and botulinum toxin during routine suture. The follow-ups were performed at 1 day, 1 week, 1 month and 3 months after operation. Vancouver Scar Scale was used to evaluate scar color, softness, blood vessel distribution and thickness, which were used to determine the hyperplasia of the scar. The postoperative satisfaction survey and adverse reaction were recorded. Results In the dye laser+botulinum toxin group, the scores of scar color, softness, thickness and vascular distribution were all lower at 1 week, 1 month and 3 months after surgery. Compared with the botulinum toxin group, the scores of scar color, softness, thickness and vascular distribution were lower in the dye laser+botulinum toxin group 1 month after operation. Three months after operation, the scores of scar color, softness and thickness were all low. Postoperative satisfaction of patients in dye laser+botulinum toxin group and botulinum toxin group was higher than that in the control group, and the incidence of adverse reactions was lower than that in the control group, which all differences were statistically significant (all P <0.05). Conclusion The 595 nm pulsed dye laser combined with botulinum toxin has relatively more effective effect on postoperative scar improvement.
