Analysis of Risk Factors and TCM Syndrome Elements of Acute Renal Injury after Surgery
YAO Zhi，SUN Lu-ying，SHI Yue-xin
Abstract:
Objective To analyze the risk factors of patients with acute renal injury after surgery and the distribution characteristics of TCM syndrome elements, so as to provide basis for early prevention and treatment. Methods The 416 patients hospitalized in the department of peripheral vascular, orthopedics and general surgery of Dongzhimen hospital of Beijing university traditional Chinese medicine from January 2016 to January 2021 were analyzed retrospectively. The patients were divided into 131 cases of postoperative acute renal injury group and 285 cases of postoperative non acute renal injury group. The general basic situation, operation related data and TCM syndrome distribution data of the two groups were collected and analyzed. The risk factors of acute renal injury after surgery were analyzed by multivariate logistic regression, and the distribution characteristics of TCM syndrome elements of acute renal injury after surgery were discussed. Results 131 patients with postoperative acute renal injury were mainly distributed in the peripheral vascular department of our hospital (76.3%), which the stage was mainly stage 1 (84%), and the etiology was mainly renal factors (53%). The disease nature of traditional Chinese medicine is mostly mixed with deficiency and excess syndrome, and the syndrome elements of deficiency syndrome are mainly Qi deficiency and blood deficiency. Blood stasis, heattoxin and damp heat are the main syndrome elements of empirical syndrome. There were signi.cant differences between the two groups in age, BMI, average length of stay, history of hypertension, history of diabetes, smoking history, hyperlipidemia, basic renal insuf.ciency, antibiotics, contrast media, preoperative creatinine, preoperative blood uric acid value, preoperative hemoglobin value, duration of operation, intraoperative blood loss and surgical classi.cation (P<0.05). Logistic regression analysis was carried out on the risk factors with signi.cant difference between the two groups. The results showed that age, hypertension, diabetes, smoking history, preoperative uric acid, basic renal insuf.ciency, antibiotics, contrast media, BMI, operative duration and intraoperative blood loss were independent risk factors for acute kidney injury after surgery. Conclusion Age, hypertension, diabetes mellitus, smoking history, preoperative serum uric acid, basic renal insuf.ciency, antibiotics, contrast media, body mass index, duration of operation and intraoperative blood loss were independent risk factors for acute kidney injury after surgery. The TCM syndrome elements of patients with acute renal injury after surgery are mainly blood stasis, heat toxin, damp heat, Qi de.ciency and blood de.ciency.
