Clinical Research of Yinchen Lidan Decoction Combined with PTCD in the Treatment of Cholangiocarcinoma with Obstructive Jaundice
XIA Zhen-wei,ZHANG Jing,GUO Tao
Department of Integrated Traditional Chinese and Western Medicine, The Third Affiliated Hospital of Chinese PLA Naval Military Medical University, Shanghai 201805, China
Abstract:
Objective The purpose of this study is to investigate the clinical efficacy of Yinchen Lidan Decoction combined with percutaneous transhepatic cholangial drainage (PTCD) in the treatment of cholangiocarcinoma with obstructive jaundice. Methods 72 cases of cholangiocarcinoma with obstructive jaundice from October 2018 to October 2020 were selected. According to the patient’s age, course of disease and bilirubin level, they were paired into control group and treatment group, which with 36 cases in each group.All patients underwent full PTCD to relieve the obstruction. At the same time, symptomatic treatments such as liver protection, anti-infection and electrolyte supplementation were given according to the condition. The treatment group was treated with Yinchen Lidan Decoction on the above basis for 14 days. Results After 14 days of treatment, the treatment group was significantly better than the control group in terms of yellowing, anorexia, fatigue, total bilirubin (TBIL), alanine aminotransferase (ALT), which KPS scores (P<0.05). The total effective rate of the treatment group is 88.9%, which is better than that of the control group of 75%. There was a difference in clinical efficacy between the two groups (P<0.05). Conclusion Yinchen Lidan Decoction combined with PTCD can not only promote bile excretion and restore liver function, but also improve patients’anorexia and fatigue.
