Analysis of Clinical Characteristics of Biliary Acute Pancreatitis and Hypertriglycerideia Induced Acute Pancreatitis
WANG Shu-jiang,ZONG He-ya
Department of Surgery,Tianjin Occupational Diseases Precaution and Therapeutic Hospital(Tianjin Workers' Hospital), Tianjin(300011), China
Abstract:
Objective To provide reference evidence for the clinical diagnosis and treatment of acute pancreatitis compared with the clinical characteristics of biliary acute pancreatitis and hypertriglyceridemia induced acute pancreatitis. Methods The medical records of 170 patients who were clinically diagnosed with acute pancreatitis from December 2018 to December 2020 at Occupational Diseases Precaution and Therapeutic Hospital were collected and analyzed. The clinical baseline data, laboratory tests, and complications of BAP and HTGAP were compared. Results In contrast to BAP, HTGAP patients had a younger median age (P<0.001), a higher BMI index (P<0.001) and more patients with fatty liver (P=0.008).White blood cell count, neutrophil count, CRP, and PCT levels w-ere significantly increased in HTGAP group (P<0.05), and serum lipid related indexes such as TG, TC and LDL-C levels were higher than those in BAP group, with statistical significance (P<0.001). However, the electrolyte status, such as blood Na+ and Ca2+ levels, were higher in the BAP group than in the HTGAP group, and the difference was statistically significant (P=0.035, P=0.004). Although there was no statistically significant difference in the total incidence of complications between the two groups (P=0.635), the incidence of pancreatic pseudocyst in the BAP group was higher than that in the HTGAP group, and the difference was statistically significant (P=0.007). Conclusion BAP and HTGAP each have distinct clinical characteristics. HTGAP is more common in young and middle-aged patients with a high BMI, dyslipidemia and other characteristics. Meanwhile, HTGAP patients are often associated with severe inflammatory reactions. In addition to inflammatory indicators in clinical treatment, blood Ca2+ also needs to be monitored regularly to evaluate the severity of the patient' s condition. For patients with BAP, early admission to hospital, perhaps reduces the incidence of pancreatic pseudocyst.
