Clinical Observation of Liquid Wound Dressing Combined with Negative Pressure Drip Irrigation in the Treatment of Diabetic Foot Infection
DU Yu-qing,LIAN Xiao-tong,LI Chuang
Department of Peripheral Vascular of Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing 100700, China
Abstract:
Objective To investigate the effectiveness of liquid wound dressing combined with negative pressure drip irrigation in the treatment of diabetic foot wound infections. Methods 80 cases of diabetic foot patients admitted to the peripheral vascular department of Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine from January 2017 to January 2019 were selected and divided into 40 cases each in the observation group and control group according to the random number method, all of which received standardised basic medical treatment. The control group was treated with negative pressure drip irrigation with a new solution of rehabilitation, and the points of wound symptoms, wound area, serum levels of IL-6, ESR and TNF-α were recorded before treatment, 2 weeks after treatment and 4 weeks after treatment in both groups. Results After 2 and 4 weeks of treatment, the wound areas of both groups were smaller than those before treatment, and the difference were statistically significant (P<0.01). After 4 weeks of treatment, the trauma area and symptom points of the observation group were significantly better than those of the control group (P<0.01). After 2 and 4 weeks of treatment, serum IL-6, ESR and TNF-α decreased in the two groups compared with those before treatment, and the difference was statistically significant (P<0.01). After 2 and 4 weeks of treatment, the levels of IL-6, TNF-α and ESR in the observation group were all smaller than those in the control group, and the difference was statistically significant (P<0.05). Conclusion Liquid wound dressing with negative pressure drip irrigation can reduce diabetic foot wound infection, improve clinical symptoms and promote wound healing.
