The Effect of Self-made Huoxue Zhitong Recipe on Bone Metabolism and Joint Recovery of Patients with Tibial Plateau Fracture
TIAN Zhong-qing
Department of orthopedic, Heze Traditional Chinese Medicine Hospital of Shandong Province, Heze 274000,China
Abstract:
Objective To evaluate the effect of self-made Huoxue Zhitong Recipe(HXZT) on postoperative treatment and rehabilitation of patients with tibial plateau fracture. Methods Seventy patients with tibial plateau fractures who received surgical treatment in our hospital from April 2018 to August 2019 were divided into two groups according to random number table. The control group(35 cases)was treated with mannitol, and the observation group(35 cases) was treated with Huoxue Zhitong recipe.The postoperative pain, changes of bone metabolic index and recovery of joint function were observed.Results The degree of swelling ten days after operation was (1.30±0.10) cm in the observation group,which was significantly lower than that in the control group(1.98 ±0.42)cm, and the VAS score was(1.48±0.22),which was significantly lower than that in the control group(1.97±0.38)(P <0.05). The average time of detumescence and analgesia in the observation group was(8.10±1.63) d and(5.30±1.03)d, which were shorter than those in the control group(9.86±2.13) d and(6.87±1.08) d respectively, The average time of fracture healing and complete weight-bearing were(90.10±13.74) d and(94.53±14.88) drespectively, which were significantly shorter than those in the control group(116.63±16.32) d and(112.45±14.45) d respectively(P <0.05). Six months after operation, the scores of Lysholm and Merchant were(53.48±3.28) and (92.63±10.53), which were higher than those of the control group (46.85±3.74) and (80.84±11.62) respectively(P<0.05). The levels of MMP-2,BMP-2 and IGF-1 in the observation group were(679.03±60.73) ng/mL, (677.05±65.28) ng/mL, (204.84±24.74) ng/mL respectively, which were higher than those in the control group (580.84 ±58.74) ng/mL, (580.88±58.94) ng/mL and (184.72±26.62) ng/mL respectively(P<0.05). The total incidence of postoperative complications was 5.71% in the observation group, which was signi?cantly lower than that of the control group(22.86%)(P<0.05). Conclusion Patients with tibial plateau fractures were treated with self-made prescription for promoting blood circulation and stopping pain after operation. It can effectively relieve the pain and swelling of the affected limb and improve bone metabolism and the effect of joint function.
