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三七活血方联合低分子肝素钙应用对THA 术后D- 二聚体的影响
冉远录
重庆市城口县中医医院外科 重庆 405900
摘要:
目的:研究三七活血方联合低分子肝素钙应用对全髋关节置换术(THA)术后D- 二聚体的影响。方法:选取2016 年1 月—2018 年12 月于我院拟行THA 的患者84 例。随机均分为联合组和对照组。对照组予以低分子肝素钙预防干预,联合组则于对照组的基础上增用三七活血方干预。比较两组术后失血量、引流量,手术前后髋关节功能变化情况,手术前后血浆D- 二聚体及凝血三项水平变化情况,以及术后下肢深静脉血栓(DVT)发生率。结果:联合组术中失血量及术后引流量均低于对照组(均P < 0.05)。术后12 天,联合组及对照组的Harris 评分均高于术前,且联合组高于对照组(均P < 0.05)。术后联合组血浆D- 二聚体、FIB 水平均低于对照组,而PT 高于对照组(均P < 0.05)。联合组术后DVT 发生率低于对照组(0 vs. 11.9%,χ2=5.316,P < 0.05)。结论:三七活血方联合低分子肝素钙可显著降低THA 术后D- 二聚体水平,同时促进患者早日康复,具有显著的预防DVT 效果,值得临床推广应用。
关键词:  全髋关节置换术  三七活血方  低分子肝素钙  D- 二聚体  深静脉血栓
DOI:10.3969/j.issn.1007-6948.2020.04.022
投稿时间:2019-12-02
基金项目:
Effect of Sanqi Huoxue Decoction Combined with Low Molecular Weight Heparin Calcium on D-dimer after THA
RAN Yuan-lu
Department of Orthopedic Surgery, Chengkou County Hospital of TraditionalChinese Medicine, Chongqing 405900, China
Abstract:
Objective To study and analyze the effect of sanqi huoxue decoction combined with low molecular weight heparin calcium on D-dimer after total hip arthroplasty (THA). Methods From January 2016 to December 2018, 84 cases of patients who planned to receive THA in our hospital were included as study objects. They were divided into combined group and control group by random draw. The control group received lowmolecular weight heparin calcium prophylaxis intervention and the combined group added sanqi huoxue decoction intervention on the basis of the control group. The postoperative blood loss, drainage volume, changes in hip function before and after operation, changes in plasma D-dimer and coagulation level before and after operation, and the incidence of DVT were compared between the two groups. Results The blood loss during surgery and postoperative drainage volume in the combined group were lower than those in the control group (both P < 0.05). The Harris scores of the combined group and the control group were higher than those of the preoperative group 12 days after the operation, and the combined group was higher than the control group (both P < 0.05). The levels of plasma D-dimer and FIB in the combined group were lower than those in the control group, while the levels of PT were higher than those in the control group (both P < 0.05). The incidence of DVT in the combined group was lower than that in the control group (P < 0.05). Conclusion Sanqi huoxue decoction combined with LMWH can significantly reduce the level of D-dimer after THA and promote the early recovery of patients, which has a significant effect of preventing DVT. It is worthy of clinical application.
Key words:  Total hip arthroplasty  Sanqi huoxue decoction  low molecular weight heparin calcium  Ddimer  deep vein thrombosis

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