Thin-layer Enhanced MR Image Analysis of 51 Cases of Intracranial Germinomas
BAI Guo-jie,ZHANG Ke-yu,ZHENG Kui-hong
Department of Radiology Tianjin Beichen Traditional Chinese Medicine Hospital, Tianjin (300400), China
Abstract:
Objective The thin-layer enhanced MR findings of intracranial germinomas, which were analyzed to improve the diagnostic accuracy. Methods A retrospective analysis of 51 cases of intracranial germinomas thin-layer enhanced MR imaging data.Divided into parts by group A (saddle region + pineal gland region), group B (around the lateral ventricle), group C (basal ganglia + thalamus region).Statistical analysis of the image characteristics and clinical data of three groups of cases (including age, gender, shape, growth pattern, border, enhancement method, degree of enhancement, pepper and salt sign, and cystic changes). Other data were tested by R * C contingency table chi-square. Results Age, 18.24 ± 4.737 years in group A; 21.68±7.888 years in group B; 19.92 ± 10.613 years in group C, P = 0.395. Gender (male: female), group A (9: 8), group B (18: 4), group C (12: 0), P = 0.010. Shape (mass: irregular), group A (16: 1), group B (22: 0), group C (0:12), P<0.001. Growth pattern (lump type: spread type), group A (17: 0), group B (0:22), group C (12: 0), P<0.001. Boundary (clear: unclear), group A (16: 1), group B (20: 2), group C (9: 3), P = 0.254. Strengthening method (uniform: uneven), group A (14: 3), group B (9:13), group C (2:12), P = 0.001. Degree of enhancement (mild: obvious), group A (16: 1), group B (19: 3), group C (11: 1), P = 0.708. Salt and pepper sign (yes:no), group A (10: 7), group B (13: 9), group C (5:7), P = 0.574. Concomitant cystic changes (yes:no), group A (7:10), group B (18: 4), group C (8: 4), P = 0.031. There were statistically signi?cant differences in gender, shape, growth pattern, strengthening pattern and concomitant cyst changes (P <0.05). There was no statistically significant difference in age, border, degree of strengthening as well as salt and pepper sign (P> 0.05). Conclusion Patients with intracranial germ cell tumor have sex, lesion shape, growth pattern, enhancement pattern and cystic changes. They are characteristics of the patient' s age, lesion boundary, degree of enhancement and different parts of the pepper-salt sign. They are familiar with intracranial germ cell tumors. MR and clinical features can improve diagnostic accuracy.
