Clinical Study on Low-pressure Negative Pressure in Treatment of Ischemia Diabetic Foot
YAN Cheng- cheng,JU Shang,HUANG Tian-yi
Peripheral Vascular Department, Dongzhimen Hospital, Beijing (100700), China
Abstract:
Objective To observe the effect of low-pressure negative pressure therapy on diabetic foot ulcer with moderate ischemia. Methods Totally 160 patients with diabetic foot ulcer with moderate ischemia were selected and divided into observation group ( 120 cases) and control group ( 40 cases) by digital table method. The patients in observation group were divided into three subgroups. The patients were treated with 120 mmHg, 90 mmHg and 60 mmHg negative pressure (intermittent mode), 40 cases in each group, to compare the ef?cacy of conventional negative pressure therapy with that of low pressure negative pressure therapy. The patients in control group were treated with routine dressing change. Wound area, local symptom score and pain score were recorded after 2 and 4 weeks of treatment. Results After 2 and 4 weeks of treatment, the effect of observation group was better than that of control group (P<0.05). There was no statistical difference in wound area and local symptom score among the three subgroups (P>0.05). In pain score, the 60 mmHg negative pressure group had the lowest pain score (2 weeks of 2.76±2.75, 4 weeks of 2.25±2.21), followed by 90 mmHg negative pressure group (2 weeks of 3.75±3.01, 4 weeks of 3.88 ±2.59). The pain score of 120 negative pressure group was the highest (2 weeks of 5.13±2.64, 4 weeks of 4.38±2.92). The difference was signi?cant (P<0.05). There was no signi?cant difference in adverse reactions among groups during treatment (P>0.05). The 60 mmHg negative pressure treatment group was the optimal treatment for this study. Conclusion Low-pressure negative pressure therapy is effective in treating diabetic ischemic foot ulcer. It can effectively promote wound healing and relieve pain of patients. It is worthy of clinical application.
